You need to setup anchors. One of my favorites is to set the pivot to 0,0 instead of 0.5,0.5 and then change the 0,0 one above to 0.5 0.5 and set the anchor to the center and then it will always be centered regardless of the resolution
anchors are key in these you need to do alot of experimentation.reading/tutorials etc. they can be complex sometimes and there is no magical answer except “anchors need to be setup properly” you can test any resolution of course with te button at the top of widget designer graph. It really depends on your layout but your buttons need to be anchored to something where they will stay in position, again generally I use the center of a border with the pivot and such changed so its centered perfectly at positon 0x and 0y and size xxxx and yyyy everytime
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