Storing large number of variables.

Ok so I’m trying to set up a Data management game.
It’s set in a shop with crafting, and hiring and so on. Now I have a lot of variables that the user can controle, many of which can be changed from multiple levels. My question is ‘what is the best way to store all this infomation?’
Should I import/export with excel and/or access, store them as global variables, or is there a better way I’m just not seeing?
I would very much appreciate some help please. Thankyou.