Rendering Broken

I run my game and the screen just broke and it flickered like crazy, after I close the preview window, the UE4 editor also flashes.

I’m running ue4 on GTX1060, I don’t know if it’s the hardware problem or what. The Scene is kind of big, I guess it’s the graphics memory problem, but it never occurred to me before. So I would like to ask what’s the matter with my project. Thanks
PS. Using HTC VR