How do i change default material in BP ?

Hey Guys i have problem. i want to add skins to my game and i need to change material of mesh which is not placed in map. i just need to change material of mesh that is in content browser

That is not possible.
You can only make changes to actors that exist in the game/level.

It is possible, all you would need to do is make sure your character selects the material (skin) they want and when the game starts make sure that the blueprints are set to change the material depending on what they had chosen previously on spawn.