Remove unneeded options

When I compile Unreal, is it possible to disable or remove things I have no need for, like Mac version, iOS, TVOS, Linux automation, one sky? If yes, what else can I remove?

Well remove is one thing, but you can just turn off the plugins you don’t plan to use. The editor has a lot going on.
with the editor made out of other editors, this lets the full program be real light in some cases, as those other editors with in are not all loaded in till its needed.
So i would just nix the plugins you don’t need and make sure if you using an Nvidia solution to have the overlay turned off.