Since the 4.4.1 hotfix, any attempt to add an instance to an instanced static mesh component will crash the editor 100% of the time. This only occurs on my Mac running OS X 10.9.4 (not my Windows 8 machine) and was not happening in 4.4.0 pre-hotfix. The crash happens regardless of the project, as it will happen even when loading the Blueprint Office example content (which uses instanced static meshes). Error output follows:
SIGSEGV: invalid attempt to access memory at address 0x3
EngineCrashHandler(FGenericCrashContext const&) Address = 0x337e68f (filename not found) [in UE4Editor]
PlatformCrashHandler(int, __siginfo*, void*) Address = 0x348866f (filename not found) [in UE4Editor-Core.dylib]
_sigtramp() Address = 0x8c6e75aa (filename not found) [in libsystem_platform.dylib]